The Implicit Genome

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Lynn Helena Caporale

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To purchase, visit your preferred ebook provider. The Implicit Genome Edited by Lynn Helena Caporale In its beautiful simplicity, the double-helicaln stucture of DNA had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. Pathogens and Disease Patrik Bavoil.

Learning to Analyze Sequences

From Field to Fork Paul B. An optimized dissimilarity score was identified from six well-studied functions based on a receiver operating characteristic ROC analysis. Based on the studies with well-studied Escherichia coli and less-studied Brucella spp. A web-based GenoMesh literature mining program is also available at: GenoMesh also predicts gene interactions and networks among genes associated with specific MeSH terms or user-selected gene lists.

Table of contents for The implicit genome

The GenoMesh algorithm and web program provide the first genome-wide, MeSH-based literature mining system that effectively predicts implicit gene-gene interaction relationships and networks in a genome-wide scope. National Center for Biotechnology Information , U. Didn't get the message?

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Add to My Bibliography. Generate a file for use with external citation management software. Images from this publication. Annual Review Microbiology Educating a New Generation. Darwin in the genome.

The Implicit Genome

Lynn Helena Caporale Independent Scholar; Lynn Caporale is a biochemist who has focused attention on evidence that natural selection can act on mechanisms that generate genome variation, much as it acts on mechanisms that create beaks and wings. Darwin in the Genome: Molecular Strategies in Biological Evolution Most descriptions of mutation have emphasized its negative consequences and randomness with respect to biological function.

Thus, chance will favour the prepared genome. The Implicit Genome Most analyses assume that genomes are to be read as linear text, much as a sequence of nucleotides can be translated into a sequence of amino acids by looking in a table. Selected Publications Caporale, L.


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