Guide Heart to Heart

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Sensors check the purity of the intermediate and final products at key stages. Such small, stand-alone pharmaceutical factories could allow drug manufacturing to be decentralized, improving access and lowering costs, the researchers write.

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Farming has fragmented the forest habitat of the Javan slow loris, but artificial bridges allow the primates to travel safely above developed land. Cautious primates called slow lorises can learn to traverse artificial bridges high above the ground, allowing the animals to move between patches of trees surrounded by farmland. That poses a threat to animals such as the critically endangered Javan slow loris Nycticebus javanicus. This primate cannot leap, so it must travel on the ground to reach unconnected trees, exposing it to predators and parasites. The primates took 13 days, on average, to venture onto the bridges, but then used them nightly.

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Lorises using the bridges added new feeding trees to their home ranges and spent less time travelling on the ground between trees. Credit: DLR. A small lander bounced repeatedly across the terrain of its target asteroid before finally coming to a rest. Frank Scholten at the Institute of Planetary Research at the German Aerospace Center in Berlin and his collaborators analysed these images to reconstruct the path of the boxy, 9.

The distance between the lander and its shadow, as well as information from instruments on the lander itself, showed that, during its minute journey from the mothership to a complete stop, MASCOT reached a speed of 0. More people in England and Canada die in hospital than at home, but in the United States, home deaths now exceed hospital deaths. For the first time since the early twentieth century, more people in the United States are dying at home than in hospitals.

Even so, by the early s, more than half of US deaths took place in hospitals. The trend favouring death outside the hospital extends to people dying of a wide variety of diseases, the researchers say. A bamboo raft designed to evoke prehistoric craft was too heavy and unwieldy for its crew to control during a test voyage off the coast of Taiwan. A failed voyage in a replica of a Stone Age boat shows that Asian mariners had better watercraft than once thought, archaeologists suggest.

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Signs of human occupation across the islands of southeast Asia and Australia suggest that Homo sapiens embarked on long-distance sea crossings before 47, years ago. Researchers had assumed that these voyages were made on crude bamboo rafts. On 11 June , a crew of 5 professional and near-professional kayakers attempted to sail the craft from Taiwan to cross the strong Kuroshio ocean current, which must have been traversed by Palaeolithic voyagers who settled the Ryukyu island chain roughly 30, years ago.

After paddling 80 kilometres in 14 hours, the kayakers abandoned the journey because of strong ocean currents and damage to the raft. Prehistoric humans must have made such voyages in sturdier boats, say the researchers, who succeeded in making the crossing in in a boat carved from a large log. Antiquity Aortic-wall tissue above generates electricity if squeezed, an attribute previously observed only in hard materials such as bone. Achilles tendons and other soft bodily tissues can produce an electric voltage when squeezed, a finding that could aid the diagnosis of some medical problems.

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Crystals, some semiconductors, dry biological tissues such as bone and other materials exhibit the piezoelectric effect, which is the ability to generate electricity when placed under mechanical stress. However, it was not clear whether soft tissues have the same property. Kenji Ikushima and his colleagues at Tokyo University of Agriculture and Technology tested for the effect in samples of aortic walls and heart valves from pigs, and Achilles tendons from cows.

The researchers induced mechanical stress in the tissues by blasting them with focused pulses of ultrasound waves. Using a tiny antenna, the team detected the resulting electromagnetic waves produced by the piezoelectric effect. The stronger the ultrasound waves and stresses, the stronger was the signal the antenna picked up. Killer-whale calves benefit from the presence of their grandmothers. Credit: Emma Foster. Daniel Franks at the University of York, UK, and his colleagues analysed more than 40 years of census data on two populations of killer whales Orcinus orca off the Pacific coast of the United States and Canada.

The researchers quantified the survival rate of calves with living or recently deceased maternal grandmothers. Calves whose maternal grandmother had died within the past two years were 4. These negative effects were more pronounced in years of food scarcity and when calves lost a grandmother that could no longer reproduce. Grandmother killer whales play a key role in helping their kin to forage, and those without calves of their own might be more likely to share food with their grandchildren, the researchers say.

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USA Rain clouds loom near Timbuktu, Mali, in the Sahara Desert, which thousands of years ago was wetter and lusher as far north as Morocco. Thousands of years ago, enough rain fell on northern Africa that the Sahara was a land of lakes instead of a desert. People hunted big animals across the green landscape and painted scenes of their triumphs on cave walls. Now, stalagmites from a Moroccan cave have revealed the full extent of this lush environment.

The stalagmites showed that the climate became rainy around 9, years ago and dry around 4, years ago. The formations confirm that the West African summer monsoon extended north to the cave — information that scientists can now use to better understand weather patterns across the region.

To explore how mitochondria communicate with the nucleus, Gerald Shadel at the Salk Institute for Biological Studies in La Jolla, California, and his colleagues dosed cells with the cancer drug doxorubicin, which damages DNA. The team altered melanoma cells to prompt their mitochondria to release more DNA. When these cells were implanted into mice, they produced tumours that survived doxorubicin treatment better than standard melanoma tumours. The scientists also put the mitochondria of engineered mice on alert and dosed these mice with ionizing radiation, which is another cancer treatment.

The engineered mice showed signs of more vigorous nuclear repair in their spleens than control mice. The results show that when damaged by a toxin or other form of abuse, the abundant mitochondrial DNA warns the nucleus that an attack is underway. This surveillance system might explain how cells acquire resistance to some DNA-targeting cancer drugs. Putting 'Edible' and 'Eatable' on the Table Giving you something to chew on.

How to remember which is which Literally How to use a word that literally drives some people nuts. Is Singular 'They' a Better Choice? The awkward case of 'his or her' Word Games Liar, Liar Quiz Test your knowledge of words for lies, liars, and those being lied to. In other words, everyone.

Winter has returned along with cold weather.


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Wrap yourself in a blanket and challenge yourself with our question quiz about words relating to winter. Can you spell these 10 commonly misspelled words? The dictionary has been scrambled—can you put it back together? Login or Register. Save Word. Log In. First Known Use of heart-to-heart Adjective , in the meaning defined above Noun , in the meaning defined above.

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