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The Omega phage will induce the pseudo-diphtheria to produce a different kind of toxin. Oh, and I'd suggest that you rethink your 2-day incubation time.

Insanity Plague - Clean the Slate (Rough Demo)

The longer the incubation, the better the chances of wide dissemination, as it muddies the epidemiological trail. With a short incubation it's easier to trace the spread of the illness, and easier to set up quarantine procedures. There's a tradeoff there - if the incubation time is too long, research on the first wave of maniacs will allow development of a vaccine before the spread becomes overwhelming.

The Plague and the Judgment

But I'd suggest that 2 days is too short. I would think it would be reasonably easy to make a bacterial disease that mimics insanity. Simply insert a gene coded to produce a hallucinogen. Some hallucinogens are natural plant products, simply copy the gene out of the plant. The hard part will be identifying the gene you need.

Syphilis gets airborne and resistant to antibiotics. Fairly short incubation period and causes degradation of mental processes. Plus, embarrassing symptoms.


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If you want a plague that causes insanity, all you have to do is aerosolize rabies. It already causes insanity, has a slow incubation time measured in weeks, not days and is The only saving grace is that it's a blood borne pathogen. Now, find some way to cross the symptoms of rabies with the spread pattern of measles and you have something truly terrifying. Simplest answer I can think of: A bacteria that produces mercury in trace amounts as it destroys blood, spinal, and brain tissue.

It could be engineered to only go after human dna so that it only affects humans. These trace amounts build up over time, and cause the bearer to go insane. The bacteria is resistant to all known forms of chemical destruction, but Radiation therapy would work. Home Questions Tags Users Unanswered. How to Design a Plague that Causes Insanity? Ask Question. Asked 4 years, 9 months ago. Active 2 years, 7 months ago. Viewed 1k times. Background: A strain of antibiotics resistant Bubonic Plague discovered in a small village was being experimented with in an effort to make it deadlier.

Question: How would I go about designing a strain of Yersinia Pestis that achieves the desired effects in the background? First, all prions are incurable, to the point where disinfecting medical instruments is near impossible. It comes in handy on Mega Brutal, especially as Nano Virus. There's also a small chance it can cause a country to nuke another or have a meltdown.

Last edited by Barry McCockinner ; 26 May, am. Originally posted by Barry McCockinner :. Insanity and paranoia could make a "totally insane" combo, making people.. You know.. Totally insane. Last edited by Cl0wnFace ; 26 May, pm. Last edited by Barry McCockinner ; 26 May, pm. Pretty sure it slows down the Cure. Originally posted by xminor1 :. Last edited by Barry McCockinner ; 28 May, pm. You can combine it with some other things and get a message that people are defacating in the streets.

I find insanity usefull in some situations. Last edited by Lord Postius ; 29 May, am. The baby dies within days.


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Delirious patients perilously wander the halls. A rumor circulates that another facility mistook one of its patients for dead, the patient screaming awake when her body was doused with bleach. Expressing a quiet indignation at the random cruelty of the disease, Hatch is effective in showing that the victims were real people. The book also reveals the logistical absurdities faced by doctors and nurses who tried to volunteer.

Perhaps most surprising, Hatch had to use his vacation days to volunteer. When he returned, the CDC advised he stay away from work for 21 days; Hatch worried about how he was going to keep his job. The theory does not have to do with epidemiology. It is possible that a careful and thoughtful writer could use these historical antecedents to enlarge our understanding of the social factors that make Africa so vulnerable to infectious disease.

Trap Door scores again with expressionistic "White Plague"

Hatch is not that writer. At every turn, Hatch assigns maximal agency to American and European actors and minimal agency to those from Africa. It is as though he is suggesting that the victims of Ebola were akin to participants in a hunger strike, albeit a mass, forced, and fatal one. That would truly have been an incredible price to pay just to teach the West a lesson.

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As the epidemic grew, numerous infectious-disease specialists warned that research on whether Ebola could be transmitted through the air, especially at close range, was fragmentary. They argued that workers treating Ebola patients should take the precaution of wearing air-filtering respirators—face-fitting masks like the ones sold in hardware stores for about two dollars to protect from paint fumes, a standard item in American hospitals. When researchers raised these concerns in medical journals, their colleagues accused them of fomenting hysteria.

Several doctors argued that CDC and WHO guidelines should not be publicly questioned or exceeded, because doing so would undermine public confidence. Some even argued that Doctors without Borders workers in West Africa should not wear full-body protective suits, as this would create the impression that the far lower infection controls in African hospitals were inadequate—which was plainly and catastrophically true. As with so many other aspects of the Ebola outbreak, the research was simply too limited for decisions on quarantines to be based on anything but guesswork. On his return layover at Dulles Airport, a few weeks after the Spencer incident, he was held in customs while officials tried to reach the Massachusetts health department on a Saturday night.

Hatch does not, even in retrospect, find any legitimate cause for his detention. This was a simple case of heroic doctor versus fear-ridden authorities. As with so many other aspects of Ebola, the research was simply too limited for decisions on quarantines to be based on anything but guesswork. Highly uncertain risks of contagion had to be balanced against temporary restrictions on freedom.