The SPSS Guide to the New Statistical Analysis of Data: by T.W. Anderson and Jeremy D. Finn (Springe

STATISTICAL. ANALYSIS. OF DATA by I.W. Anderson and Jeremy D. Finn .. T. W. Anderson et al., The SPSS Guide to the New Statistical Analysis of Data average, on the verbal portion of the test than do those who take it in the spring.
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BART is a computerized task in which participants earn hypothetical money by incrementally increasing the size of a balloon. The dependent variable was average number of pumps, excluding balloons that popped Lejuez et al. Drug severity was determined using a dimensional approach by adding abuse and dependence symptom counts across all drugs Gelhorn et al.

Dependent variables were inspected for normality. For normally-distributed variables, one-way ANCOVAs, adjusted for education which differed between controls and patients but not between SD and SDPG , were performed with post-hoc comparisons between each two group combination e.

SDPG when indicated by a significant group effect. Categorical variables were analyzed with chi-square and Fisher Exact tests, as recommended Campbell, For variables that were not approximately normally distributed, Kruskal-Wallis tests were performed and when the group effect was significant, post-hoc comparisons between each two-group combination were conducted with Mann-Whitney U tests.

When normally-distributed variables demonstrated non-homogenous variability, a reciprocal transformation was performed.

What happened?

Demographic data are shown in Table 1. Controls had more education than SD controls Controls had higher IQ than SD controls Because of these group differences education was entered as a covariate in the analyses that included the control group i. Post-hoc analysis revealed that controls passed on bad decks more than SD controls Post-hoc analysis revealed significant differences between controls and SD controls 0. Post-hoc analysis revealed significant differences between controls and SD controls Post-hoc analysis revealed controls reported less impulsivity than both SD controls Figure 2 shows discounting curves for each group, estimated from averaging hyperbolic curves fit to each subject.

There were no significant group differences in average number of pumps, excluding balloons that popped Controls: Drug severity did not correlate with other variables i. These results suggest that among substance users, a co-occurring diagnosis of pathological gambling may be a marker for greater deficits in decision-making and more drug-related symptoms. We found significant differences between all three groups on decision-making performance.

Prior work has shown impaired passing on bad decks in substance dependent individual compared to control Thompson et al. We extend that work by showing for the first time that co-occurring PG further impairs performance. A caveat is that these samples partially overlapped. The current sample size of participants has greater power to examine the effect of PG compared to the prior study of 58 participants.

To evaluate the cognitive processes that underlie decision-making, we implemented a computational model of the Iowa Gambling Task Stout et al. Our results are consistent with Stout et al. We extend those results and suggest that compared to substance dependence alone, those with co-occurring pathologic gambling are even less sensitive to loss and less consistent in their decision-making choices.


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The most notable difference between our study and those that found no difference is in the criteria for gambling and substance use problems. Drug severity was measured using a dimensional approach Gelhorn et al. Compared to SD, SDPG had significantly greater drug severity, in spite of the fact that, except for cannabis, dependence diagnoses were not significantly different between the groups. In addition, impulsivity correlated with drug severity and is consistent with the notion that greater impulsivity is associated with a worse clinical course. While our study cannot determine causality e.

This indicates that regardless of the causal relationships, high levels of impulsivity are likely to persist even with sustained full remission in a controlled environment. Our data support a recommendation to assess for co-morbid pathological gambling in substance abuse treatment populations, given the very high rates of co-morbidity and because SDPG individuals differ from SD patients in clinical meaningful ways.

A co-occurring diagnosis of pathological gambling should raise the clinician's concern for very high levels of impulsiveness that may require more intensive intervention. As new treatments to improve forms of impulsiveness are developed, this patient population may particularly benefit. We demonstrate two negative findings that require comment. The lack of a statistical difference across the 3 groups may reflect differences in demographics. Petry and Casarella did not adjust for a point difference in IQ between non-problem gamblers with and without substance abuse.

Moreover, a comparison of controls to all substance users e. Inconsistent results may reflect differences in delay discounting tasks and analyses Reynolds, Previous studies compared groups by fitting hyperbolic curves to estimate discounting rates. This analysis assumes that the data fit a hyperbolic curve, though this assumption is not necessarily true. This method would have excluded nearly one-third of our data, suggesting that discounting in our participants did not meet this assumption.

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Thus, our primary analysis measured AUC which does not assume the data are hyperbolic. We found no group differences on BART, a measure of risk-taking. Other studies have also shown mixed results using this task in patients with substance use disorders Lejuez et al. Not providing real monetary rewards for behavior on the BART may have reduced the sensitivity of this task. Here we show that patients with both diagnoses demonstrate even greater decision-making impairment, impulsiveness, and drug use severity.

The decision-making impairment may be driven by greater insensitivity to loss and choice inconsistency.


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  • It is possible that both disorders are manifestations of an underlying behavioral disinhibitory trait. Traits such as antisocial behavior, impulsivity, risk-taking, and issues in personality and temperament may signify an overall problem in behavioral control. For example, early problems with behavioral control have predicted adult SD risk Moffitt et al. Our study was limited by the lack of a group with pathological gambling without substance dependence. The SDPG group was relatively small compared to the other groups; however, it is representative of gambling disorders in patients with substance dependence.

    Unequal group size can affect the homogeneity of the sample. To prevent violating assumptions for parametric analyses, nonparametric analyses were utilized when necessary and variables were transformed to homogenize variability among groups. In conclusion, individuals with substance dependence and pathological gambling have poorer decision-making, driven by low sensitivity to loss and response inconsistency, than substance dependent individuals without pathological gambling.

    These characteristics are measurable in the laboratory, appear to persist even after years of abstinence, and suggest targets at which to direct treatment. Furthermore, pathological gambling is prevalent among substance dependent individuals in treatment and associated with more drug-related symptoms. Our results suggest that when evaluating patients with substance use, clinicians should also consider diagnostic assessments for gambling problems.


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    • PhD for helping with the model. This project was funded by grants DA and DA All other authors declare they have no conflicts of interests. National Center for Biotechnology Information , U. Author manuscript; available in PMC Jul 1. Theodore Krmpotich , B. Jody Tanabe, MD, E. The publisher's final edited version of this article is available at J Addict Med.

      See other articles in PMC that cite the published article. Abstract Objectives Substance use disorder is characterized by impaired decision-making, impulsivity, and risk-taking. Conclusions Compared to individuals with substance dependence without pathological gambling, those with both disorders demonstrated worse decision-making and significantly more drug-related symptoms.

      Structured Interviews All interviews and assessments were administered by trained lay personnel on two separate days. Data analysis Dependent variables were inspected for normality. Results Demographics Demographic data are shown in Table 1. Table 1 Means and Standard Deviations for demographic data, drug dependence, and abstinence.

      Open in a separate window. Table 2 Behavioral and cognitive measures. Balloon Analogue Risk Task There were no significant group differences in average number of pumps, excluding balloons that popped Controls: Footnotes Conflict of Interest Drs.

      Data Analysis in SPSS Made Easy

      Diagnostic and statistical manual of mental disorders. Delay and probability discounting in pathological gamblers with and without a history of substance use problems. Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey. Chi-squared and Fisher-Irwin tests of two-by-two tables with small sample recommendations. Pathological and problem gambling in substance use treatment: J Subst Abuse Treat.

      Adolescent brain development, risk-taking and vulnerability to addiction.

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