Fate and Consequences

Fate and Consequences has ratings and 29 reviews. Sheila said: 12/20/ I have again reread this book - usually a few pages or a chapter at bedtime.
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However, the vast majority of gene duplicates are silenced within a few million years, with the few survivors subsequently experiencing strong purifying selection.


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Although duplicate genes may only rarely evolve new functions, the stochastic silencing of such genes may play a significant role in the passive origin of new species. We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. By Michael Lynch , John S.


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You are currently viewing the abstract. Log in to view the full text via AAAS login. Register for free to read this article As a service to the community, this article is available for free. I decided to re-read this book and I don't know what I was thinking when I wrote my original review of "I adored this book. This is what I want in a Pride and Prejudice variation. This is a book of melodrama and sex. A very long book - pages. As I re-read it I would glance at my meter on the Kindle and think 'Really I decided to re-read this book and I don't know what I was thinking when I wrote my original review of "I adored this book.

As I re-read it I would glance at my meter on the Kindle and think 'Really?? Can this not just end' Now if you like your Pride and Prejudice what ifs with a heaping helping of Penthouse letters then this is the book for you. If not read on This what if starts with Darcy missing Georgiana at Ramsgate and having to her track down. Fitzwilliam discover her in Meryton. Here they interact with Elizabeth Bennet who gives Miss Darcy a handkerchief.

Darcy is determined to return the item. As Georgina's elopement becomes known he becomes more depressed. He decides to keep the handkerchief and sends replacements and a note. He and Lizzy begin corresponding. This is whiny, weepy, emo Darcy. As the story progresses we learn that his home life at Pemberley was terrible with his parents constant fighting and then taking lovers view spoiler [Georgiana isn't a Darcy hide spoiler ]. When one of Lizzy's letters goes astray he goes on bender and locks himself in his study. Meanwhile in Meryton Lizzy is having her own problems.

John Lucas has decided he will marry her and won't take no for an answer. And of course Mr. Wickham is on the prowl. When Darcy finally arrives at Netherfield he and Lizzy are deeply in love. He proposes, she accepts. We learn that his sister was ruined as a teenager and the scandal led to his parents premature deaths and his loveless marriage to Fanny Gardiner. Yes Lizzy also grew up in household with no love between her parents. When Darcy brings Georgiana to Netherfield he is hopeful that her disgrace will be unknown.

The evolutionary fate and consequences of duplicate genes. - PubMed - NCBI

Alas Wickham is close by and spreads the story with many elaborations that omit his involvement. With the accidental assistance of a 'Crazy Caroline' Georgiana is insulted and verbally attacked in Meryton. Then she and Lizzy are taken hostage by Wickham. Darcy and Lizzy all but anticipate their vows, many times in disturbing detail.

And beyond my personal sensitivities to this I find it a ridiculous plot point. Darcy is a few months from his sister's ruin by merely eloping with Wickham and Mrs. I cannot believe that he would be so willing to expose Lizzy to the same censure. Regardless of their plans to marry he is taking a dangerous risk and in one case relying upon Jane to assist them. And then it just goes on and on and on. Mar 16, Elizabeth Bennet rated it really liked it. This book read similar to Wells other books she has written on our couple. In this one Fitzwilliam is desperate to save his sister from Wickham.

Part victory is his in saving his sister before completely ruined but she does not get away without witness and unfortunately young Georgiana is the subject of many rumors throughout the ton. During the tragedy Georgiana finds a friend in Elizabeth and carries over to Darcy. He immediately finds himself under her spell, but this is not the proud, fastid This book read similar to Wells other books she has written on our couple. He immediately finds himself under her spell, but this is not the proud, fastidious Darcy we all know. Some may not like the change to his personality, but I enjoyed him very much.

He was raised by no adoring mother in love with his father. Anne Darcy was completely made over and it trickled down onto his father and greatly effected our William. He rises above all this to save his sister. It is so sweet to see how he throws away what society would think and for the love of a sister strove to protect and keep her close. That was one of my favorite impacts this book held on me. The other was how the author once again pulls you into her Darcy and Elizabeth relationship. This one added a nice spin on things due to another suitor. John Lucas is determined to turn Lizzy's head even if it means he must compromise her.

It is one villain after another as Wickham, Lucas and family, Caroline and an aunt who won't let things go. Don't worry while your on your seats edge Darcy's devotion to those he loves is something to behold. Richard has some spot light shed on him as he courts an unsuspected love interest. I enjoyed that twist but would have enjoyed some more time spent between them. I also enjoyed Lizzy's mother in this one.

This is a Mrs. Bennet that inspires Darcy to call her mother.

What is the difference between consequence and fate?

I also like the side story of Mr. Bennet and his disowned sister. Her likeness to a lively, expressive eyed woman was also interesting. The book for the length went fast and made me want to keep reaching for it. Its about a man never thinking to marry after living through his parents miserable marriage. Falling in love through kindness and love letters which I always enjoy. I admired Darcy refusing to cast Georgiana off and how protective he was over not only her but also anyone else he loved.

Some may not like the change to the characters and the explicit love scenes but if you are willing to not let that stop you it really is a delightful read. This like the 40th time I've read this book and I still love it. Apr 30, Amy rated it did not like it Shelves: In general, I love Jane Austen spin-offs, but there were pages and pages of just words. I stuck with it longer than I should have because of its 4. I really enjoyed the divergent path this storyline took from the original, it gave us a look at what might have happened if Georgiana had been considered ruined by the ton and how Darcy may have dealt with that.

My biggest issue with this story was that is just kept going. There was trial after trial for Darcy and Elizabeth to overcome, and just when you thought they were finally in the clear one more comes along! And there were so many secondary characters and their own little storylines that kept popping in and out, that it ended up dragging a bit. I did enjoy Wells' treatment of Mrs. Bennett and her relationship with Mr. Bennett, and quite enjoyed seeing a more playful side of Mr. Apr 30, Hannah M. Georgiana Darcy and George Wickham have been discovered by her brother and cousin at an inn in Meryton.

Though the two tried to reach her before leaving Ramsgate in order to prevent any word of the elopement spreading they were unsuccessful. The Darcy family is thrown into a scandal and Georgiana is ruined. Though I have seen other people say that this particular variation was not as good as others, I thoroughly enjoyed it. I really liked how Linda Wells took the relationship of Darcy and Elizabeth, building it up and strengthening them from a moment of weakness to a strong family. Apr 16, Alexandra rated it really liked it Shelves: This book is a big improvement over Chance Encounters.

She has really polished up her writing quite a bit Well, it is, but not as much as in CE. As with her first book, this one is chock-full of bodice ripping purists, beware! Some of it is quite graphic, but the writing of these love scenes has FAR more finesse than her first novel did. Again, as with her first book, she writes about Darcy and Elizabeth meeting, through their courtship, marriage, and a few years thereafter.

I haven't come across another author who writes the whole shebang; it's either about their courtship or about their married life. The story is very interesting up until their marriage I also need to note that while the editing was generally quite improved, there was a distinct dearth of commas throughout. Jun 12, Nicol Legakis rated it liked it Shelves: One complaint I have is that Darcy is made out to be a bit too weak and fragile.

Darcy doesn't have an insecure bone in his body! On a positive note, this book explains the realities of what happened to a woman who was "ruined" back in the eighteenth and nineteenth century. This positive attribute of the book however, is in direct contrast with Darcy's treatment of Elizabeth. In this adaptation he has an extreme concern for his sister's ruin, and a supposedly complete devotion to Elizabeth. I don't think he would have come even close to the way he behaved in this novel regarding his inappropriate show of "affection" for Elizabeth and total lack of restraint knowing full well the ruin that would fall upon Elizabeth and all of her family if she were caught in a compromising position.

It was well written but a bit disappointing. Sep 20, Charlotte added it. Anyone who uses double exclamation points in a novel should stick to writing emails!! Would you believe that the author also used double question marks?? That is to say nothing about of course dear reader the hundreds of missing commas.

A competent proofreader would have made a big difference in this one. The author was also quite heavy-handed in charcterization and frequently tone-deaf with respect to the history, both in terms of using anachronistic language and in terms of the poor grasp of c Anyone who uses double exclamation points in a novel should stick to writing emails!!

The author was also quite heavy-handed in charcterization and frequently tone-deaf with respect to the history, both in terms of using anachronistic language and in terms of the poor grasp of culture. The book is just not remotely subtle, about anything.


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Points are to be awarded here for the interesting premise and the fact that I really wanted it to be better--it was so close to compelling sometimes. Aug 18, Dianna Anderson rated it liked it. This had so much promise. It sucked me in immediately and kept me interested fully for the first two thirds of it. I will be honest though, the last third was a struggle to read. I don't know if it was just that the book was way too long or it just lost the excitement in the end. This site uses cookies to deliver our services and to show you relevant ads and job listings. By using our site, you acknowledge that you have read and understand our Cookie Policy , Privacy Policy , and our Terms of Service.

I've noticed that some premade digital GM screens I've used say that consequences give you -2, -4 and -6 to your attack value, but can't seem to find this in the core book. Is this just something I'm misunderstanding, or does it mean that if you, for example, get a mild consequences of "dazed", does your attack value get a -2 on it?

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The GM screen you're reading is probably alluding to the rules for resolving attacks in a conflict — specifically the part where if someone lands an attack on you, you can "reduce the shift value of the attack" as the rules put it by taking a consequence, e. Having that consequence provides no ongoing direct penalty to your actions or attacks. As you found when you went to the Fate Core book, consequences which you have taken do not give you a minus to your subsequent attacks.

In fact, there is nothing at all in Fate Core which has a mechanical effect like that. Modifiers are always positive.