Guide Trapped in Ecstasy

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Ecstasy has long been a favourite at trance parties and raves because of its unique ability to flood users with intense feelings of euphoria. But as a byproduct, it also reduces fear and imbues users with a deep sense of love and acceptance of themselves and others - the perfect conditions for trauma therapy. By giving doses of MDMA at the beginning of three, eight-hour therapy sessions, researchers say they have helped chronic PTSD patients process and move past their traumas.

In clinical trials with patients closely monitored by the FDA, 61 percent reported major reductions in symptoms - to the point where they no longer fit the criteria for PTSD. Follow-up studies a year later found 67 percent no longer had PTSD. Doblin, now 63, talks openly about his own history with drugs. He began tripping on LSD as a rebellious, long-haired college freshman in the s. He says it helped him see the world and himself in new ways.

He wanted to become a therapist and use psychedelics to help others achieve similar insights, but he couldn't because LSD was already banned. Culture is always going to win. For a decade, he worked in construction until he came across MDMA for the first time. The lawsuit failed, and Doblin realised that psychedelics were perceived as too fringe to win public support. Doblin talked his way into the public policy PhD programme at Harvard University and learned to navigate the federal bureaucracy.

He shaved off his moustache, cut his shaggy hair and learned to dress up. The external switch reflected an internal one as well. Instead of fighting government officials, he began plotting to win them over, especially those at the FDA. Previous studies suggesting its neurotoxicity had been limited to rats.


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So in , Doblin scraped together money to buy monkeys for those same researchers, who found the risks to be much less at human-equivalent doses than previously thought. The next step was investigating MDMA's effects on people. Doblin again raised money to fly psychedelic users he had befriended to Stanford University and Johns Hopkins University for spinal taps. The studies were approved by review boards at both institutions. Doblin also participated, undergoing two spinal taps.

MDMA seems like proof that what comes up must come down.

The nonprofit grew from a one-man band to a staff of 25 with headquarters in Santa Cruz. It tapped into the scene in Silicon Valley - where many tech entrepreneurs have used psychedelics to spark creativity. Steve Jobs famously praised LSD as "one of the two or three most important things I have done in my life.

Much of that money funded small-scale clinical trials, which laid the groundwork for the last remaining hurdle: Large-scale "phase 3" trials that will begin next year, involving to patients in 14 locations. Yet his dream extends beyond that. He envisions a future where psychedelic treatment centres are in every city - places people can visit for enhanced couples therapy, spiritual experiences and personal growth.

He believes psychedelics can help address the country's biggest problems, from homelessness and war to global warming.

The horror that should put everyone off Ecstasy

It's hard to measure the exact dangers of ecstasy. Because it is not used as widely as marijuana or cocaine, for example, fewer statistics are available on overdoses or injuries. In , a public health monitoring system identified 22, emergency department visits nationwide related to ecstasy.

MDMA researchers point out that one key difference between MDMA and street ecstasy along with another variant called "molly" is the street versions often contain other harmful drugs, experts say. Sometimes the pills don't even contain MDMA. But even in its purest clinical form, MDMA can pose risks.


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    • At high doses, it can cause the body to overheat. It can cause anxiety and increase the stress hormone cortisol. Chronic use can also cause memory impairment. MAPS still isn't seen as mainstream. But it's possible they have a point here," said Krystal, the Yale psychiatrist, who has not been involved with the group's research. The question here is whether the benefits outweigh the risk. The Marine Corps and Army veteran recalls coming home from Iraq in to discover his wife had left him, sold his motorcycle and taken his dog.

    That, coupled with the trauma of what he had saw at war, sent him over the edge.

    Ecstasy May Make Octopuses Cuddly

    On Christmas Eve, he put the muzzle of his Beretta to his temple and pulled the trigger. The gun malfunctioned, he said, "but that microsecond after the hammer fell is when I finally felt at peace because I knew the pain would finally be over. One incident in Iraq in particular tormented him - a shot he took while protecting his unit. After he was accepted into the MDMA clinical trial in South Carolina, he found himself on a futon with two counselors on either side as the effects of the drug sank in.

    Since then, he said, he has learned to accept what happened in Iraq. And the guilt he now struggles with is the fact he got chosen over others for the clinical trial. But they can't do it because it's illegal. This could save their lives. You can find our Community Guidelines in full here. Want to discuss real-world problems, be involved in the most engaging discussions and hear from the journalists?

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