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21 Anti-Aging Secrets From the World's Most Beautiful Women. Posted by Samantha Speisman on March 13, , Updated February 16, "Looking good is about eating right, getting enough sleep, and drinking lots of water." She also I live by the 80 percent rule: I try to be percent good 80 percent of the time.".
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USA , — Bogan, K. MacKay, D. Niacin: chemical forms, bioavailability, and health effects. Bitterman, K. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1. Guan, X. Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies.

PLoS One. Trammell, S. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.

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Mills, K. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Frederick, D. Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle.

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell 15 , — Sato, S. Circadian reprogramming in the liver identifies metabolic pathways of aging. Cell , —66 Chi, Y. Nicotinamide riboside, a trace nutrient in foods, is a Vitamin B3 with effects on energy metabolism and neuroprotection. Care 16 , — Imai, S. A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis. Ratajczak, J. NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.

Houtkooper, R. Chobanian, A. Whelton, P. Laurent, S. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Heart J. Tunaru, S. Benyo, Z. Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells. Carlson, L. Nicotinic acid: the broad-spectrum lipid drug.

A 50th anniversary review.

Bieganowski, P. Wright, J. A randomized trial of intensive versus standard blood-pressure control. Hyattsville, MD: U. Hardy, S. Reducing the blood pressure-related burden of cardiovascular disease: impact of achievable improvements in blood pressure prevention and control. Heart Assoc. Materson, B. Prehypertension is real and can be associated with target organ damage. Pase, M. Aortic stiffness and the risk of incident mild cognitive impairment and dementia. Stroke 47 , — Chue, C. Arterial stiffness in chronic kidney disease: causes and consequences. Heart 96 , — Ochi, M. Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men.

Atherosclerosis , — Abbatecola, A. Pulse wave velocity is associated with muscle mass decline: Health ABC study. Age 34 , — Mitchell, G. Arterial stiffness and hypertension chicken or egg? Hypertension 64 , — Dernellis, J. Aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive subjects. Hypertension 45 , — Kaess, B.

Aortic stiffness, blood pressure progression, and incident hypertension. Mattagajasingh, I. SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase. Gao, D. Hypertension 68 , — Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice.

Evans, C. BMC Chem. Tanaka, H. Arterial stiffness and hormone replacement use in healthy postmenopausal women. A Biol. Absence of age-related increase in central arterial stiffness in physically active women.

Eskurza, I. Ascorbic acid does not affect large elastic artery compliance or central blood pressure in young and older men. Heart Circ. Moreau, K. Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women.

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Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study. Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women. Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. Jablonski, K.

Walker, A. Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor kappa B. Kaplon, R. Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults. Bell, C. Oxidative stress does not modulate metabolic rate or skeletal muscle sympathetic activity with primary aging in adult humans. Thermogenic responsiveness to beta-adrenergic stimulation is augmented in exercising versus sedentary adults: role of oxidative stress.

Bergman, R. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. DeVan, A. Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. DeSouza, C. Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Reuben, D. Motor assessment using the NIH Toolbox. Neurology 80 , S65—S75 Justice, J.

Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults. Aging 7 , — Lunsford, B. The standing heel-rise test for ankle plantar flexion—criterion for normal. Vestergaard, S. Stopping to rest during a meter walk and incident mobility disability in older persons with functional limitations. Cho, B. Tests of stepping as indicators of mobility, balance, and fall risk in balance-impaired older adults.