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In e-learning settings, blogs and micro-blogs can plausibly provide a platform to conduct PBL Mobile devices are more powerful and portable nowadays with plenty of useful tools for assisting people to handle daily life. With the advance of mobile technology, the issue of mobile learning has been widely investigated in e-learning research If mobile learning is to be effectively developed and feasibly applied to education, it is necessary to evaluate its effectiveness. This study adopted Herrington's nine elements of authentic learning paradigm to develop an authentic learning-based OpenCourseWare was integrated into the flipped classroom model experimental group and distance Is it feasible to hold concurrent, small-group, peer-managed discussions in large elementary school classes?

We sought an initial answer to this question in a fifth-grade class in Hefei, China. The 52 students in the class were divided into seven The purpose of this study was to explore the impact of Digital storytelling DST on the academic achievement, critical thinking, and learning motivation of senior high school students learning English as a foreign language. The one-year study This study is aimed to discuss the scientific concept formation and zone of proximal development ZPD of preschool children of foreign marriage. As the number of foreign marriage in Taiwan becomes steady in recent years, subsequent issues, such as Facebook is currently the most popular social networking service in the world.

With such tremendous influence on community networks, Facebook has been attracting considerable attention both from the media and academia. A review of the literature However, in traditional education, students learn these two important subjects in separate courses. This study proposes a Researchers have conducted various studies on applying wireless communication and ubiquitous computing technologies to education, so that the technologies can provide learners and educators with more active and adaptive support.

This study proposes The development of collocational knowledge is important for foreign language learners; unfortunately, learners often have difficulties producing proper collocations in the target language. Among the various ways of collocation learning, the DDL The theory of spatial thinking is relevant to the learning and teaching of many academic domains.

Background

One promising method to facilitate learners' higher-order thinking is to utilize a web map mind tool to assist learners in applying spatial thinking to This paper briefly reports the outcomes of an action research inquiry on the use of blogs, MS PowerPoint [PPT], and the Internet as learning tools with a science class of sixth graders for project-based learning.

Multiple sources of data were In recent years, using video as a learning resource has received a lot of attention and has been successfully applied to many learning activities. In comparison with text-based learning, video learning integrates more multimedia resources, which Studies in clinical medicine have demonstrated that the neurotransmitters released when students increase their physical activities make students more concentrated and stabilized, and this may lead to satisfactory academic performance.


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To reduce effectively the reading anxiety of learners while reading English articles, a C4. The system supports elementary students in the The purpose of this study was to develop an explanatory model for the information and communication technology ICT competencies of students with and without learning disabilities LD. A conceptual model was proposed, and included five major Recent studies on digital game based learning have applied the flow theory to explain the immersion of students in game playing. However, the relationship Visitors to Taipei also have the opportunity to experience firsthand how the flourishing of design education in Taiwan over the last twenty years has fostered creativity around the city.

Printed in both book and brochure form, the publication highlights 70 iconic design locations and 12 walking routes around the city, which are arranged into six themes: the Architecture Stroll, Select Shops, Original Delicacy, Old Houses, Handicraft Fun, and Design Hotels. Select shops, such as Mogu, Sunset, and 30Select, display the refined tastes and eco-friendly inclinations of local creative types.

Transcendent Elder Mao

In May, tourists can also witness social design in action as the city transforms itself for the World Design Capital Taipei Upcoming events include the Taipei Design, Action! Follow-up data were obtained from medical records and referring physicians, and survival data were updated every six months. Overall survival OS was calculated from the date of surgery to the date of death. Disease-specific survival DSS was measured from the date of surgery to the date of known cancer-related death. Pathologic CR was defined as the absence of any tumor cells in the operative pathologic specimen, at the primary site and in lymph node regions.

Descriptive statistics were used to describe. Chi-square tests were performed to determine significant univariate predictors of pCR. All identified significant continuous predictors in univariate analysis were further categorized as corresponding dichotomous variables and each cutoff value was determined by implementing a corresponding binary recursive partition in a conditional inference framework [15].

Anemia as an Independent Predictor of Adverse Cardiac Outcomes in Patients with Atrial Fibrillation

The criterion in a conditional inference framework is to maximize the 1 minus P-value. Next, a multivariate logistic regression analysis was then used to identify the significant multivariate predictors of pCR. This was continued until only significant variables remained.


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The final results of a multivariate logistic regression were expressed in odds ratios and confidence intervals. Finally, sstimated pCR rates were obtained by the logistic regression using all possible combinations of significant predictors. Survival curves were plotted using the Kaplan-Meier method. All statistical analyses were performed using SPSS The general characteristics of the entire cohort were summarized in Table 1. There were males and 10 females with the mean age of Most of the tumors occurred in the middle-third of the esophagus The pretreatment mean tumor length was 6.

Fifty-nine The Ivor-Lewis procedure was used in individuals and 48 patients were treated with the Mackeown procedure. Three patients received exploratory surgery without resection due to intraoperatively identified T4 or M1 disease. For reconstruction, the stomach was used in cases and colon interposition in 7 cases. In-hospital mortality occurred in 16 cases. The median OS was The baseline demographic features differed significantly between groups.

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As shown in Table 1, the pCR group of patients were on average older, fewer had a history of smoking or alcohol use and more had a history of hypertension HTN. With respect to the pre-nCRT parameters, patients in the pCR group had a significantly shorter tumor length on average. In order to improve clinical utility, significant continuous variables selected from univariate analysis age and tumor length were further transformed onto an ordinal scale before entering them into a multivariate analysis based on a recursive partition.

Neoadjuvant CRT is currently in widespread use as the first-line treatment for locally advanced esophageal cancer [3]. It has become increasingly evident that only patients with a good response pCR or near pCR after nCRT have a survival benefit, whereas for those with little response after nCRT, survival is invariably poor [].

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In non-responders, a valuable therapeutic window may have been lost, the patient may have unnecessarily experienced severe CRT toxicity, and may even have lost the opportunity to have potentially curative surgery [7]. Thus, reliable predictive factors for pCR are of great clinical importance. In the current study, we have analyzed a number of potential predictive factors for pCR in esophageal cancer of the.

Although we did not evaluate molecular markers, our study is distinguished by its large size and the incorporation of multiple common clinical parameters.

Echocardiographic evaluation

We identified three predictive factors for pCR - age, smoking status and tumor length - all of which are easily measureable and, hence, easily verifiable in large-scale trials. These factors may ultimately form the basis for a practical predictive marker for routine clinical use. Smoking is a well-known risk factor for esophageal cancer [16]. However, few reports directly evaluate smoking as a prognostic factor for esophageal cancer, or. In our study, we found that smoking was a statistically significant, negative predictor for pCR. Although the mechanism by which smoking reduces the efficacy of CRT is still unknown, overexpression of DNA repair enzymes because of smoking is one possibility.

Increased expression of a DNA repair enzyme was reported in heavy smokers with esophageal cancer or non-small cell lung cancers and was also associated with a poor response to CRT [19,20]. Taken together, these reports might explain the poor response to CRT in patients with a heavy smoking habit in our study. However, the importance of tumor length was outweighed by the depth of invasion from onwards because of their strong inter-correlation [21].

A growing number of studies since then have re-confirmed that tumor length is an indicator of more aggressive behavior independent of T stage [22,23]. Our findings suggest that tumor length might also predict the response to CRT, an observation that could potentially be. Old age was not a significant prognostic factor for esophageal carcinoma in most studies but was identified as a predictor for pCR in the current study [25]. The reasons for this are unclear and may relate to a complex set of interactions.

In Taiwan, earlier age-onset esophageal cancer represents a unique cohort; these patients are more frequently associated with habitual use of substances tobacco, alcohol or areca nut seed of the Areca palm that are known to reduce the response to radiotherapy [26].